Note that the architecture of these studies has been alleged into question, and some still accede (liposomal) amphotericin B as the biologic of choice.
Importantly, voriconazole aswell offered a 22% greater adaptation account over amphotericin B, with 71% of voriconazole patients still animate at anniversary 12. Alone 13% of patients who accustomed antecedent analysis with voriconazole died from invasive aspergillosis, compared with 29% of patients who initially accustomed amphotericin B.
For assorted website or CNS aspergillosis a aggregate analysis of voriconazole and caspofungin should be considered. It is aswell the recommended analysis for the CNS fungal infections transmitted by epidural bang of attenuated steroids.
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