IL-11 was originally abandoned from beef acquired from the hematopoietic microenvironment and may act as a paracrine or autocrine advance agency in this environment.
IL-11 acts synergistically with added early- and late-acting advance factors to activate assorted stages and lineages of hematopoiesis.147 In synergy with IL-3, Il-4, IL-7, IL-12, IL-13, SCF, flt-3 ligand, and GM-CSF, IL-11 stimulates the admeasurement of archaic axis beef and their charge in to multi-lineage ancestors as able-bodied as their differentiation.
The accessory furnishings of IL-11 and TPO on multi-lineage beef may be advised in allotment by SCF/c-kit interactions.
more about: IL-11 ELISA Kit
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